SCHEMBL7789733

SCHEMBL7789733

CCC(=O)CC(=O)C(=O)O.[Cr]

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HAO1 Q9UJM8 2/20 0.52
TDP1 Q9NUW8 2/20 0.47
FFAR3 O14843 1/20 0.40
OR51E2 Q9H255 2/20 0.36
FEN1 P39748 4/20 0.34
ERCC5 P28715 3/20 0.34
PTPN1 P18031 1/20 0.34
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
SLC13A3 Q8WWT9 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
ALOX15 P16050 1/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL891538 0.97 HAO1 (0.54) HAO1TDP1FFAR3OR51E2FEN1
SCHEMBL27675640 0.94 HAO1 (0.52) HAO1TDP1FFAR3OR51E2FEN1
SCHEMBL27523190 0.94 HAO1 (0.52) HAO1TDP1FFAR3OR51E2FEN1
SCHEMBL11186408 0.94 HAO1 (0.52) HAO1TDP1FFAR3OR51E2FEN1
SCHEMBL7798107 0.79 HAO1 (0.65) HAO1FFAR3OR51E2ALDH1A1MAPK1
SCHEMBL247453 0.76 HAO1 (0.68) HAO1FFAR3OR51E2ALDH1A1MAPK1
SCHEMBL7796552 0.75 HAO1 (0.80) HAO1TDP1OR51E2PTPN1ALDH1A1
SCHEMBL93369 0.75
SCHEMBL6522626 0.74 TDP1 (0.50) HAO1TDP1FFAR3ALDH1A1ALOX15
SCHEMBL6522609 0.74 TDP1 (0.50) HAO1TDP1FFAR3ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4146694-A CHROMIUM CATALYST, SUPPORT ACTIVATED WITH ZIRCONIUM COMPOUND, OLEFIN POLYMERS CHEMPLEX COMPANY (US) 1979-03-27 US claimed
US-4128500-A CHROMIUM CHELATE DISPERSED ON A ZIRCONIUM MODIFIED SUPPORT ENRON CHEMICAL COMPANY 1978-12-05 US claimed
US-3953413-A ACTIVATION BY HEAT TREATMENT CHEMPLEX COMPANY (US) 1976-04-27 US claimed
EP-0808849-B1 Process for the production of ethylenic polymers SHOWA DENKO KK (JP) 2001-12-19 EP disclosed
US-6326443-B1 COORDINATION POLYMERIZATION CATALYST SHOWA DENKO K.K. (JP) 2001-12-04 US disclosed
US-6011127-A CATALYST COMPRISING A CHROMIUM COMPOUND, AN ALUMOXANE AND AN ORGANOMETALLIC ALKOXIDE AND/OR ORGANOMETALLIC SILOXIDE AND A CARRIER SUPPORTING THEREON THESE COMPOUNDS. SHOWA DENKO K.K. (JP) 2000-01-04 US disclosed
EP-0931797-A1 PROCESS FOR PREPARING ETHYLENE POLYMER AND CATALYST USED THEREFOR SHOWA DENKO KABUSHIKI KAISHA (JP) 1999-07-28 EP disclosed
EP-0763550-B1 Ethylenic polymerization catalyst SHOWA DENKO KK (JP) 1999-05-06 EP disclosed
US-5723399-A CHROMIUM COMPOUND, ALUMOXANE, TRANSITION METAL COMPOUND SHOWA DENKO K.K. (JP) 1998-03-03 US disclosed
EP-0808849-A1 Process for the production of ethylenic polymers SHOWA DENKO KABUSHIKI KAISHA (JP) 1997-11-26 EP disclosed
EP-0763550-A1 Ethylenic polymerization catalyst SHOWA DENKO KABUSHIKI KAISHA (JP) 1997-03-19 EP disclosed