SCHEMBL7240672

SCHEMBL7240672

CCC/C=C/c1ccc(Cc2ccc(CCC)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNNC1 P63316 1/20 0.44
LTA4H P09960 1/20 0.39
KDM4E B2RXH2 1/20 0.38
MITF O75030 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
KLF5 Q13887 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
LPL P06858 1/20 0.37
LIPG Q9Y5X9 1/20 0.37
PLK1 P53350 1/20 0.37
HTR1D P28221 1/20 0.37
SPHK1 Q9NYA1 2/20 0.36
THRB P10828 2/20 0.36
SPHK2 Q9NRA0 1/20 0.35
CA2 P00918 1/20 0.35
MGLL Q99685 1/20 0.33
HDAC8 Q9BY41 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7240675 1.00 TNNC1 (0.44) TNNC1LTA4HKDM4EMITFALDH1A1
SCHEMBL27618886 0.94 TNNC1 (0.48) TNNC1KDM4EMITFALDH1A1HPGD
SCHEMBL7237159 0.92 TNNC1 (0.47) TNNC1KDM4EMITFALDH1A1HPGD
SCHEMBL7237164 0.92 TNNC1 (0.47) TNNC1KDM4EMITFALDH1A1HPGD
SCHEMBL7239329 0.89 TNNC1 (0.52) TNNC1LTA4HKDM4EALDH1A1CYP4F2
SCHEMBL7239330 0.89 TNNC1 (0.52) TNNC1LTA4HKDM4EALDH1A1CYP4F2
SCHEMBL7230297 0.89 TNNC1 (0.48) TNNC1KDM4EMITFALDH1A1HPGD
SCHEMBL7228828 0.89 TNNC1 (0.48) TNNC1KDM4EMITFALDH1A1HPGD
SCHEMBL7230293 0.89 TNNC1 (0.48) TNNC1KDM4EMITFALDH1A1HPGD
SCHEMBL7228822 0.89 TNNC1 (0.48) TNNC1KDM4EMITFALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6623810-B2 Refractive index anisotropy SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-09-23 US disclosed
US-20010050353-A1 Phenylacetylene compound, liquid crystal composition, and liquid crystal element produced with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-12-13 US disclosed
EP-0781827-B1 Liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL CO (JP) 2001-06-13 EP disclosed
US-6149837-A SUBSTITUTED 1,4-BIS(SUBSTITUED PHENYLACETYLENE)BENZENE WHERE AT LEAST ONE RING HAS AN ALKYL ATTACHMENT, HAS A LARGE ANISOTROPY OF REFRACTIVE INDEX, TENDS TO BE MIXED WITH OTHER LIQUID CRYSTALS, IS LIGHT STABLE; LIQUID CRYSTAL ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-11-21 US disclosed
US-5866035-A LARGE BIREFRINGENCE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-02 US disclosed
EP-0781827-A1 Liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-02 EP disclosed