Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925630 | 0.87 | C1S (0.55) | C1SPLAU | |
| SCHEMBL6926375 | 0.85 | C1S (0.54) | C1SPLAU | |
| SCHEMBL7242120 | 0.83 | C1S (0.65) | C1SPLAU | |
| SCHEMBL7246060 | 0.81 | CCR2 (0.52) | C1SPLAU | |
| SCHEMBL7248368 | 0.81 | C1S (0.53) | C1S | |
| SCHEMBL7669987 | 0.80 | MCL1 (0.44) | C1S | |
| SCHEMBL6925664 | 0.79 | C1S (0.62) | C1SPLAU | |
| SCHEMBL6928674 | 0.78 | C1S (0.69) | C1SPLAU | |
| SCHEMBL6926242 | 0.77 | C1S (0.56) | C1SPLAU | |
| SCHEMBL6927266 | 0.77 | C1S (0.63) | C1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562840-B1 | Non-peptidic inhibitors of proteolytic enzymes such as urokinase | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-05-13 | — | — | US | claimed |
| US-6291514-B1 | Heteroaryl amidines, methylamidines and guanidines, preparation thereof, and use thereof as protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2001-09-18 | — | — | US | claimed |