⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14907243 | 0.75 | — | — | |
| SCHEMBL2298573 | 0.68 | — | — | |
| SCHEMBL14886971 | 0.67 | — | — | |
| SCHEMBL15974268 | 0.63 | APP (0.30) | — | |
| SCHEMBL14040449 | 0.62 | — | — | |
| SCHEMBL19594509 | 0.62 | — | — | |
| SCHEMBL15974584 | 0.62 | APP (0.33) | — | |
| SCHEMBL2755819 | 0.60 | HRH3 (0.33) | — | |
| SCHEMBL1581091 | 0.58 | — | — | |
| SCHEMBL21375610 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240336617-A1 | Substituted Bimane Compounds and Methods of Use Thereof | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2024-10-10 | — | — | US | disclosed |
| US-6613456-B2 | Organic thin layer film containing a 1,5-diazabicyclo(3,3,0)octa-3, 5-diene-2,8-dione derivatives | NEC CORPORATION (JP) | 2003-09-02 | — | — | US | disclosed |
| US-20020041978-A1 | Organic thin layer film containing a 1,5-diazabicyclo(3,3,0)octa-3, 5-diene-2,8-dione derivatives | SAMSUNG DISPLAY CO., LTD. (KR) | 2002-04-11 | — | — | US | disclosed |
| US-6322908-B1 | PYRAZOLOPYRAZOLEDIONE HOLE TRANSPORT COMPOUND, E.G., 3,4,6,7-TETRAMETHYL-1,5-DIAZABICYCLO(3,3,0)OCTA-3,5-DIEN-2,8-D IONE | NEC CORPORATION (JP) | 2001-11-27 | — | — | US | disclosed |
| US-4499284-A | FLUORESCENCE, PHOSPHORESCENCE LABELS | TEL AVIV UNIVERSITY (IL) | 1985-02-12 | — | — | US | disclosed |
| EP-0018991-A4 | 1,5-DIAZABICYCLO(3.3.0)OCTADIENEDIONE DERIVATIVES, PREPARATION AND USE THEREOF AS FLUORESCENT LABELLING AGENTS. | KOSOWER EDWARD M (IL) | 1981-03-24 | — | — | EP | disclosed |
| EP-0018991-A1 | 1,5-DIAZABICYCLO(3.3.0)OCTADIENEDIONE DERIVATIVES, PREPARATION AND USE THEREOF AS FLUORESCENT LABELLING AGENTS | KOSOWER, Edward, M. (IL) | 1980-11-26 | — | — | EP | disclosed |
| WO-1980000565-A1 | 1,5-DIAZABICYCLO(3.3.0)OCTADIENEDIONE DERIVATIVES,PREPARATION AND USE THEREOF AS FLUORESCENT LABELLING AGENTS | KOSOWER E (US) | 1980-04-03 | — | — | WO | disclosed |