SCHEMBL2298573

SCHEMBL2298573

CC1=NNC(=O)C1(Br)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14040449 0.73
SCHEMBL7240887 0.68
SCHEMBL19594509 0.59
SCHEMBL2755819 0.57 HRH3 (0.33)
SCHEMBL6731032 0.49
SCHEMBL9026634 0.48
SCHEMBL14446948 0.47
SCHEMBL2200799 0.45
SCHEMBL10830637 0.45 TSHR (0.32)
SCHEMBL2107618 0.45 TSHR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111116475-A Synthesis method of α dibromide of α -heterocyclic carbonyl compound 中国药科大学 2020-05-08 CN disclosed
US-20140018379-A1 PYRIMIDINE DERIVATIVES CONCERT PHARMACEUTICALS INC. (US) 2014-01-16 US disclosed
US-20140018379-A1 PYRIMIDINE DERIVATIVES CONCERT PHARMACEUTICALS INC. (US) 2014-01-16 US disclosed
US-8410124-B2 Deuterated etravirine CONCERT PHARMACEUTICALS INC. (US) 2013-04-02 US disclosed
US-8410124-B2 Deuterated etravirine CONCERT PHARMACEUTICALS INC. (US) 2013-04-02 US disclosed
US-8410124-B2 Deuterated etravirine CONCERT PHARMACEUTICALS INC. (US) 2013-04-02 US disclosed
EP-2212298-B1 DEUTERATED ETRAVIRINE CONCERT PHARMACEUTICALS INC (US) 2013-03-27 EP disclosed
EP-2536696-A1 PYRIMIDINE DERIVATIVES Concert Pharmaceuticals Inc. (US) 2012-12-26 EP disclosed
WO-2011103457-A1 PYRIMIDINE DERIVATIVES CONCERT PHARMACEUTICALS INC. (US) 2011-08-25 WO disclosed
WO-2011103457-A1 PYRIMIDINE DERIVATIVES CONCERT PHARMACEUTICALS INC. (US) 2011-08-25 WO disclosed
US-7192691-B2 Method of manufacturing light sensitive planographic printing plates and method of using the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-03-20 US disclosed
US-7192691-B2 Method of manufacturing light sensitive planographic printing plates and method of using the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-03-20 US disclosed
US-7172851-B2 Light sensitive composition, planographic printing plate material, and image formation method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-02-06 US disclosed
US-7172851-B2 Light sensitive composition, planographic printing plate material, and image formation method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-02-06 US disclosed
US-7169535-B2 Photosensitive composition and photosensitive lithographic printing plate KONICA MINOLTA HOLDINGS, INC. (JP) 2007-01-30 US disclosed
US-7169535-B2 Photosensitive composition and photosensitive lithographic printing plate KONICA MINOLTA HOLDINGS, INC. (JP) 2007-01-30 US disclosed
US-20070015086-A1 Photosensitive composition, photosensitive planographic printing plate material, and image forming method of photosensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2007-01-18 US disclosed
US-20070015086-A1 Photosensitive composition, photosensitive planographic printing plate material, and image forming method of photosensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2007-01-18 US disclosed
US-20070009831-A1 PLANOGRAPHIC PRINTING PLATE MATERIAL AND IMAGE FORMATION METHOD KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-11 US disclosed
US-20070009831-A1 PLANOGRAPHIC PRINTING PLATE MATERIAL AND IMAGE FORMATION METHOD KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-11 US disclosed