Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7240247 | 1.00 | HTT (0.39) | HTTGAAL3MBTL1CA1CA2 | |
| SCHEMBL7848573 | 0.87 | HTT (0.32) | HTTGAAL3MBTL1TSHR | |
| SCHEMBL7895954 | 0.85 | CTSL (0.40) | HTTGAAL3MBTL1CA1CA2 | |
| SCHEMBL7853547 | 0.84 | CYP1A2 (0.35) | — | |
| SCHEMBL7230115 | 0.77 | CYP1A2 (0.36) | — | |
| SCHEMBL4321037 | 0.77 | CYP1A2 (0.36) | — | |
| SCHEMBL9556257 | 0.76 | CA1 (0.43) | HTTGAAL3MBTL1CA1CA2 | |
| SCHEMBL9556255 | 0.76 | CA1 (0.43) | HTTGAAL3MBTL1CA1CA2 | |
| SCHEMBL7237675 | 0.76 | — | — | |
| SCHEMBL23749270 | 0.72 | CA1 (0.41) | HTTL3MBTL1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518305-B1 | For inhibiting neuraminidases from disease- causing microorganisms, especially, influenza neuraminidase | ABBOTT LABORATORIES | 2003-02-11 | — | — | US | disclosed |