SCHEMBL724145

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL723027	0.90	PTGES (0.47)	SYKPDE4CPTGESALOX5BRD4
	SCHEMBL723616	0.85	PDE4C (0.53)	SYKPDE4CPTGESALOX5BRD4
	SCHEMBL723585	0.84	PDE4C (0.51)	SYKPDE4CPTGESALOX5BRD4
	SCHEMBL16817243	0.82	PDE4C (0.50)	SYKPDE4CPTGESALOX5CYP1A1
	SCHEMBL724141	0.82	PDE4C (0.48)	SYKPDE4CPTGESALOX5BRD4
	SCHEMBL10267652	0.81	CYP1A1 (0.54)	SYKPDE4CPTGESALOX5CYP1A1
	SCHEMBL724037	0.81	RPS6KA2 (0.43)	SYKPDE4CPTGESALOX5BRD4
	SCHEMBL723093	0.80	PDE4C (0.55)	SYKPDE4CPTGESALOX5BRD4
	SCHEMBL722271	0.80	PDE4C (0.48)	SYKPDE4CPTGESALOX5BRD4
	SCHEMBL722596	0.80	PDE4C (0.50)	SYKPDE4CPTGESALOX5BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.