Acetic Acid

Acetic Acid

SCHEMBL724155

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nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.33
GRIK2 Q13002 1/20 0.33
FFAR3 O14843 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
CTH P32929 1/20 0.31
GABRR1 P24046 2/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL293963 0.85
Hydrochloric Acid SCHEMBL28041693 0.83
Acetic Acid SCHEMBL2164879 0.80 GRIK1 (0.42) GRIK1GRIK2FFAR3LCKFYN
Acetic Acid SCHEMBL2392018 0.80 FFAR3 (0.44) GRIK1FFAR3LCKFYNGABRR1
Acetic Acid SCHEMBL3402077 0.80 FFAR3 (0.44) GRIK1FFAR3LCKFYNGABRR1
SCHEMBL27009125 0.74
SCHEMBL15772329 0.74 GRIK1 (0.35) GRIK1GRIK2GABRR1
Acetic Acid SCHEMBL10583204 0.73 FFAR3 (0.37) GRIK1FFAR3LCKFYNGABRR1
Acetic Acid SCHEMBL9752533 0.73 SLC1A3 (0.38) GRIK1FFAR3LCKFYNGABRR1
Acetic Acid SCHEMBL17060542 0.73 SLC1A3 (0.38) GRIK1FFAR3LCKFYNGABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2625257-A1 CLEANING EFFICACY OF METAL-SAFE SOLID FOR AUTOMATED INSTRUMENT PROCESSING Ecolab Inc. (US) 2013-08-14 EP claimed
WO-2012045365-A1 CLEANING EFFICACY OF METAL-SAFE SOLID FOR AUTOMATED INSTRUMENT PROCESSING ECOLAB INC. (US) 2012-04-12 WO claimed
EP-3077492-A1 CLEANING COMPOSITION WITH RAPID FOAM COLLAPSE Rohm and Haas Company (US) 2016-10-12 EP disclosed
WO-2015084610-A1 CLEANING COMPOSITION WITH RAPID FOAM COLLAPSE ROHM AND HAAS COMPANY (US) 2015-06-11 WO disclosed
WO-2014060018-A1 LOW FOAMING RINSE AID COMPOSITION WITH IMPROVED DRYING AND CLEANING PERFORMANCE ECOLAB INC. (US) 2014-04-24 WO disclosed
EP-2625257-A1 CLEANING EFFICACY OF METAL-SAFE SOLID FOR AUTOMATED INSTRUMENT PROCESSING Ecolab Inc. (US) 2013-08-14 EP disclosed
EP-2609185-A1 LIQUID CLEANER FOR AUTOMATED INSTRUMENT PROCESSING Ecolab Inc. (US) 2013-07-03 EP disclosed
WO-2012045365-A1 CLEANING EFFICACY OF METAL-SAFE SOLID FOR AUTOMATED INSTRUMENT PROCESSING ECOLAB INC. (US) 2012-04-12 WO disclosed
WO-2012025160-A1 LIQUID CLEANER FOR AUTOMATED INSTRUMENT PROCESSING ECOLAB INC. (US) 2012-03-01 WO disclosed