Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL31288570 | 0.89 | GRIK1 (0.47) | GRIK1GRIK2CYP2C19SLC6A2SLC6A4 | |
| SCHEMBL504520 | 0.83 | — | — | |
| Acetic Acid SCHEMBL859882 | 0.83 | GRIK1 (0.40) | GRIK1GRIK2CYP2C19SLC6A2SLC6A4 | |
| SCHEMBL28199815 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL9073585 | 0.81 | — | — | |
| Acetic Acid SCHEMBL724155 | 0.80 | GRIK1 (0.33) | GRIK1GRIK2FFAR3LCKFYN | |
| Acetic Acid SCHEMBL3402077 | 0.78 | FFAR3 (0.44) | GRIK1ALDH1A1FFAR3LCKFYN | |
| Acetic Acid SCHEMBL2392018 | 0.78 | FFAR3 (0.44) | GRIK1ALDH1A1FFAR3LCKFYN | |
| Acetic Acid SCHEMBL31261309 | 0.76 | GRIK1 (0.59) | GRIK1GRIK2CYP2C19 | |
| Acetic Acid SCHEMBL1160861 | 0.74 | GRIK1 (0.42) | GRIK1GRIK2CYP2C19SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082064-A1 | CHELATING AGENT MODIFIED GRAPHENE OXIDES, METHODS OF PREPARATION AND USE | MONTCLAIR STATE UNIVERSITY (US) | 2011-07-07 | — | — | WO | claimed |
| US-9133034-B2 | Chelating agent modified graphene oxides, methods of preparation and use | JINING LEADERNANO TECH L.L.C. (CN) | 2015-09-15 | — | — | US | disclosed |
| US-20120330044-A1 | CHELATING AGENT MODIFIED GRAPHENE OXIDES, METHODS OF PREPARATION AND USE | MONTCLAIR STATE UNIVERSITY (US) | 2012-12-27 | — | — | US | disclosed |
| WO-2011082064-A1 | CHELATING AGENT MODIFIED GRAPHENE OXIDES, METHODS OF PREPARATION AND USE | MONTCLAIR STATE UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |
| US-6235704-B1 | BIODEGRADABLE | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | disclosed |
| US-6225278-B1 | CHELATING AGENTS; EFFICIENCY | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120330044-A1 | CHELATING AGENT MODIFIED GRAPHENE OXIDES, METHODS OF PREPARATION AND USE | SCO2, AOC1, AOX1 | GRIK1 802/4885GRIK2 1452/4885CYP2C19 2500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.