SCHEMBL7242183

SCHEMBL7242183

CCCCCC(CC)CN1C(=O)C2C3C=CC(C3)C2C1=O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.50
KMT2A Q03164 3/20 0.49
RAB9A P51151 2/20 0.49
MEN1 O00255 2/20 0.49
HTT P42858 2/20 0.46
TSHR P16473 2/20 0.46
USP2 O75604 1/20 0.46
HSD17B10 Q99714 1/20 0.46
KDM4E B2RXH2 2/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
LMNA P02545 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
MAPK1 P28482 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
PKM P14618 1/20 0.41
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28502493 0.99 KMT2A (0.51) ALDH1A1KMT2ARAB9AMEN1HTT
SCHEMBL31372460 0.96 ALDH1A1 (0.51) ALDH1A1KMT2ARAB9AMEN1HTT
SCHEMBL29911378 0.96 ALDH1A1 (0.51) ALDH1A1KMT2ARAB9AMEN1HTT
SCHEMBL159735 0.96 ALDH1A1 (0.51) ALDH1A1KMT2ARAB9AMEN1HTT
SCHEMBL29414004 0.96 ALDH1A1 (0.51) ALDH1A1KMT2ARAB9AMEN1HTT
SCHEMBL28369465 0.88 ALDH1A1 (0.56) ALDH1A1KMT2ARAB9AMEN1HTT
SCHEMBL28373159 0.87 ALDH1A1 (0.51) ALDH1A1KMT2ARAB9AMEN1HTT
SCHEMBL28513627 0.87 ALDH1A1 (0.56) ALDH1A1KMT2ARAB9AMEN1HTT
SCHEMBL28373239 0.84 ALDH1A1 (0.51) ALDH1A1KMT2ARAB9AMEN1HTT
SCHEMBL28369624 0.84 ALDH1A1 (0.53) ALDH1A1KMT2ARAB9AMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0133406-B1 CYCLOPROPANECARBOXYLIC-ACID DERIVATIVES, THEIR PREPARATION, THEIR USE AS PARASITICIDES AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1987-04-22 EP claimed
US-4569928-A UNSATURATED CYCLOPROPANE CARBOXYLIC ACID DERIVATIVES ROUSSEL UCLAF (FR) 1986-02-11 US claimed
US-4210671-A Abietamide derivatives, their production and use ENOMOTO HIROSHI (JP) 1980-07-01 US claimed
CN-111770964-B Resin composition and electronic component 日本瑞翁株式会社 2022-12-02 CN disclosed
CN-114402258-A Radiation-sensitive resin composition 日本瑞翁株式会社 2022-04-26 CN disclosed
CN-108779317-B Resin composition, resin film, and electronic component 日本瑞翁株式会社 2021-04-16 CN disclosed
CN-107922742-B Resin composition 日本瑞翁株式会社 2021-01-15 CN disclosed
CN-111770964-A Resin composition and electronic component 日本瑞翁株式会社 2020-10-13 CN disclosed
CN-106104380-B Radiation-sensitive resin composition and electronic component 日本瑞翁株式会社 2020-03-06 CN disclosed
US-20030008913-A1 Derivatives of 2,2-dimethyl 3(2-fluoro vinyl) cyclopropane carboxylic acid, their preparation process and their use as pesticides ADAMS ANDREW (DE) 2003-01-09 US disclosed
EP-1042272-A1 DERIVATIVES OF 2,2-DIMETHYL 3-(2-FLUORO VINYL) CYCLOPROPANE CARBOXYLIC ACID, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES Aventis CropScience GmbH (DE) 2000-10-11 EP disclosed
US-4356187-A INSECTICIDES ROUSSEL UCLAF (FR) 1982-10-26 US disclosed
US-4315943-A Cyclopropyl-carboxylates used as nematocides ROUSSEL UCLAF (FR) 1982-02-16 US disclosed
US-4315012-A 3-Tetrahaloethyl-cyclopropane-1-carboxylate esters ROUSSEL UCLAF (FR) 1982-02-09 US disclosed
US-4296091-A (S)AND(L)1-OXO-2-ALLYL-3-METHYL-CYCLOPENT-2-EN-4-YL CHRYSANTHEMATE ROUSSEL UCLAF (FR) 1981-10-20 US disclosed
EP-0018894-A1 Esters of allethrolone derivatives and carboxylic acids, process for their preparation and the compositions containing them ROUSSEL-UCLAF (FR) 1980-11-12 EP disclosed
US-4231932-A PESTICIDES ROUSSEL UCLAF (FR) 1980-11-04 US disclosed
EP-0017526-A1 Compositions active against arthropodes containing a synergistic combination of esters of (S)-allethrolone and (R)-allethrolone ROUSSEL-UCLAF (FR) 1980-10-15 EP disclosed
US-4136195-A INSECTICIDAL CYCLOPROPANE CARBOXYLATES ROUSSEL UCLAF (FR) 1979-01-23 US disclosed
US-4133826-A REACTION OF OPTICALLY ACTIVE OR RACEMIC MIXTURE OF ESTERS WITH BASE ROUSSEL UCLAF (FR) 1979-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030008913-A1 Derivatives of 2,2-dimethyl 3(2-fluoro vinyl) cyclopropane carboxylic acid, their preparation process and their use as pesticides DDT, CYP2E1, CYP4F2 ALDH1A1 117/4885KMT2A 1387/4885RAB9A 1431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.