Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | TACR2 | P21452 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27820336 | 0.98 | PTGS2 (0.48) | CAPN1PTGS2CYP3A4ESR1ADRA2A | |
| SCHEMBL152937 | 0.98 | PTGS2 (0.48) | CAPN1PTGS2CYP3A4ESR1ADRA2A | |
| SCHEMBL27839490 | 0.98 | PTGS2 (0.48) | CAPN1PTGS2CYP3A4ESR1ADRA2A | |
| SCHEMBL150002 | 0.98 | PTGS2 (0.48) | CAPN1PTGS2CYP3A4ESR1ADRA2A | |
| SCHEMBL9190829 | 0.98 | PTGS2 (0.48) | CAPN1PTGS2CYP3A4ESR1ADRA2A | |
| SCHEMBL27839562 | 0.98 | PTGS2 (0.48) | CAPN1PTGS2CYP3A4ESR1ADRA2A | |
| SCHEMBL982395 | 0.98 | PTGS2 (0.48) | CAPN1PTGS2CYP3A4ESR1ADRA2A | |
| SCHEMBL147400 | 0.98 | PTGS2 (0.48) | CAPN1PTGS2CYP3A4ESR1ADRA2A | |
| SCHEMBL981785 | 0.98 | PTGS2 (0.48) | CAPN1PTGS2CYP3A4ESR1ADRA2A | |
| SCHEMBL27820016 | 0.98 | PTGS2 (0.48) | CAPN1PTGS2CYP3A4ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113636968-B | Synthetic method of 3-acyl pyrrole compound | 南通大学 | 2023-03-03 | — | — | CN | claimed |
| CN-113636968-A | Synthetic method of 3-acyl pyrrole compound | 南通大学 | 2021-11-12 | — | — | CN | claimed |
| CN-112382746-B | Preparation method of lithium ion battery anode material with heat closing and self-healing functions | 湖南省正源储能材料与器件研究所 | 2021-04-23 | — | — | CN | claimed |
| CN-112382746-A | Preparation method of lithium ion battery anode material with heat closing and self-healing functions | 湖南省正源储能材料与器件研究所 | 2021-02-19 | — | — | CN | claimed |
| CN-108503572-B | Synthetic method of 3-acyl pyrrole compound | 河南师范大学 | 2021-02-02 | — | — | CN | claimed |
| US-9968587-B2 | Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-05-15 | — | — | US | claimed |
| US-20160200678-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-07-14 | — | — | US | claimed |
| US-20120208086-A1 | PROCESS FOR COATING FINE PARTICLES WITH CONDUCTIVE POLYMERS | DEFENSE THREAT REDUCTION AGENCY; DEPT. OF DEFENSE; UNITED STATES GOVERNMENT | 2012-08-16 | — | — | US | claimed |
| EP-1979916-B1 | CHEMICAL DEFUNCTIONALIZATION OF POLYMERIC ALKYLENEDIOXYHETEROCYCLICS | UNIV FLORIDA (US) | 2012-03-21 | — | — | EP | claimed |
| US-20080175992-A1 | Process For Coating Fine Particles With Conductive Polymers | CHEMETALL GMBH (DE) | 2008-07-24 | — | — | US | claimed |
| US-4904687-A | Fungicidal substituted 3-arylpyrroles | BAYER AKTIENGESELLSCHAFT (DE) | 1990-02-27 | — | — | US | claimed |
| EP-0300312-A2 | Substituted 3-aryl pyrroles | BAYER AG (DE) | 1989-01-25 | — | — | EP | claimed |
| US-4002643-A | REARRANGING WITH A STRONG, ANHYDROUS, NON-OXIDIZING ACID | MCNEIL LABORATORIES, INC. (US) | 1977-01-11 | — | — | US | claimed |
| JP-1034958-A | — | — | None | — | — | JP | disclosed |
| JP-5086024-A | — | — | None | — | — | JP | disclosed |
| JP-5086025-A | — | — | None | — | — | JP | disclosed |
| EP-0277537-A1 | 1-Aminomethyl-3-aryl-4-cyano-pyrrole | BAYER AG (DE) | 1988-08-10 | — | — | EP | disclosed |
| JP-S63166878-A | FULGIDE BASED PHOTOCHROMIC COMPOUND | YAMAHA CORP | 1988-07-11 | — | — | JP | disclosed |
| JP-S61275123-A | METHOD FOR DISPROPORTIONING HALOGENATED SILANE | MITSUI TOATSU CHEM INC | 1986-12-05 | — | — | JP | disclosed |
| US-4002643-A | REARRANGING WITH A STRONG, ANHYDROUS, NON-OXIDIZING ACID | MCNEIL LABORATORIES, INC. (US) | 1977-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200678-A1 | HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO | CACNG1, VIPR1, CAP1 | CAPN1 42/4885PTGS2 1797/4885CYP3A4 4376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.