Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | TSHR | P16473 | 6/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | TYMS | P04818 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31158232 | 0.91 | ALDH1A1 (0.65) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 | |
| SCHEMBL3630203 | 0.91 | ALDH1A1 (0.65) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 | |
| SCHEMBL28712139 | 0.89 | ALDH1A1 (0.62) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 | |
| SCHEMBL29518611 | 0.89 | ALDH1A1 (0.62) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 | |
| SCHEMBL18600581 | 0.88 | HSD17B10 (0.58) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 | |
| SCHEMBL14742902 | 0.83 | ALDH1A1 (0.59) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 | |
| SCHEMBL29613364 | 0.83 | HSD17B10 (0.68) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 | |
| SCHEMBL4851942 | 0.83 | HSD17B10 (0.68) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 | |
| SCHEMBL29568709 | 0.83 | HSD17B10 (0.68) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 | |
| SCHEMBL29569839 | 0.83 | HSD17B10 (0.68) | HSD17B10ALDH1A1HPGDTSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030108892-A1 | Irradiation of pyrene and dimethyl aniline in water, forming labels for oligonucleotides, proteins, ceramics, transistors, semiconductors, insulators, or glass | THE UNIVERSITY OF MANCHESTER (GB) | 2003-06-12 | — | — | US | disclosed |
| EP-1242360-A2 | EXCIPLEXES | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001046121-A2 | EXCIPLEXES | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 2001-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030108892-A1 | Irradiation of pyrene and dimethyl aniline in water, forming labels for oligonucleotides, proteins, ceramics, transistors, semiconductors, insulators, or glass | MDM4, PHAX, DIMT1 | HSD17B10 4815/4885ALDH1A1 4658/4885HPGD 3528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.