Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 11/20 | 0.61 |
| ▸ | CDK8 | P49336 | 11/20 | 0.61 |
| ▸ | CDK19 | Q9BWU1 | 11/20 | 0.61 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCND3 | P30281 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15104759 | 0.89 | CCNC (0.79) | CCNCCDK8CDK19DRD2DRD4 | |
| SCHEMBL7247724 | 0.88 | CCNC (0.55) | CCNCCDK8CDK19DRD2DRD4 | |
| SCHEMBL7242256 | 0.87 | CCNC (0.58) | CCNCCDK8CDK19DRD2DRD4 | |
| SCHEMBL7250302 | 0.87 | CCNC (0.64) | CCNCCDK8CDK19DRD2DRD4 | |
| SCHEMBL7246810 | 0.86 | CCNC (0.77) | CCNCCDK8CDK19DRD2DRD4 | |
| SCHEMBL7242865 | 0.86 | CCNC (0.54) | CCNCCDK8CDK19DRD2DRD4 | |
| SCHEMBL7036281 | 0.86 | CCNC (0.59) | CCNCCDK8CDK19DRD2DRD4 | |
| SCHEMBL7249230 | 0.85 | CCNC (0.55) | CCNCCDK8CDK19DRD2DRD4 | |
| SCHEMBL15104780 | 0.85 | CCNC (0.52) | CCNCCDK8CDK19DRD2DRD4 | |
| SCHEMBL7038710 | 0.85 | CCNC (0.54) | CCNCCDK8CDK19DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030158245-A1 | Fused heterocyclic derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158245-A1 | Fused heterocyclic derivatives, their production and use | TST, STS, AHR | CCNC 2012/4885CDK8 3614/4885CDK19 2184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.