⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7234243 | 0.93 | — | — | |
| SCHEMBL7234315 | 0.93 | — | — | |
| SCHEMBL7234201 | 0.92 | — | — | |
| SCHEMBL7240616 | 0.89 | ALDH1A1 (0.54) | — | |
| SCHEMBL7231811 | 0.87 | — | — | |
| SCHEMBL10469605 | 0.86 | — | — | |
| SCHEMBL10470709 | 0.84 | — | — | |
| SCHEMBL10469597 | 0.84 | — | — | |
| SCHEMBL7234883 | 0.83 | — | — | |
| SCHEMBL7762866 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6531476-B1 | Block multiplication of virus within body and restore immune functions by virtue of inhibitory activity toward platelet activating factor | UNIVERSITE PARIS 7 - DENIS DIDEROT (FR) | 2003-03-11 | — | — | US | claimed |
| EP-1095029-B1 | PIPERAZINE DERIVATIVES INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | UNIV PARIS 7 DENIS DIDEROT (FR) | 2002-09-18 | — | — | EP | claimed |
| EP-1095029-A1 | PIPERAZINE DERIVATIVES INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | UNIVERSITE PARIS 7 - Denis DIDEROT (FR) | 2001-05-02 | — | — | EP | claimed |
| WO-2000001677-A1 | PIPERAZINE DERIVATIVES INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | UNIVERSITE PARIS 7 - DENIS DIDEROT (FR) | 2000-01-13 | — | — | WO | claimed |
| US-20250000821-A1 | METHODS OF USING DIPIVEFRIN | Insignis Therapeutics, Inc. | 2025-01-02 | — | — | US | disclosed |
| US-20240358634-A1 | AURIS FORMULATIONS FOR TREATING OTIC DISEASES AND CONDITIONS | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2024-10-31 | — | — | US | disclosed |
| US-11969501-B2 | Auris formulations for treating otic diseases and conditions | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2024-04-30 | — | — | US | disclosed |
| US-20240074995-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES | FIRST WAVE BIO, INC. | 2024-03-07 | — | — | US | disclosed |
| US-11918653-B2 | Triglyceride otic formulations and uses thereof | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2024-03-05 | — | — | US | disclosed |
| US-11793777-B2 | Methods and compositions for treating conditions associated with an abnormal inflammatory response | FIRST WAVE BIO, INC. (US) | 2023-10-24 | — | — | US | disclosed |
| US-11744812-B2 | Methods of treatment | FIRST WAVE BIO, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| US-20230201143-A1 | METHODS OF TREATMENT | FIRST WAVE BIO, INC. | 2023-06-29 | — | — | US | disclosed |
| US-20220193010-A1 | METHODS OF USING DIPIVEFRIN | INSIGNIS THERAPEUTICS INC (US) | 2022-06-23 | — | — | US | disclosed |
| US-20220105057-A1 | METHODS OF TREATMENT | FIRST WAVE BIO, INC. | 2022-04-07 | — | — | US | disclosed |
| US-20220079897-A1 | METHODS OF TREATMENT | FIRST WAVE BIO, INC. | 2022-03-17 | — | — | US | disclosed |
| US-20220040095-A1 | AURIS FORMULATIONS FOR TREATING OTIC DISEASES AND CONDITIONS | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2022-02-10 | — | — | US | disclosed |
| US-6531476-B1 | Block multiplication of virus within body and restore immune functions by virtue of inhibitory activity toward platelet activating factor | UNIVERSITE PARIS 7 - DENIS DIDEROT (FR) | 2003-03-11 | — | — | US | disclosed |
| EP-1095029-B1 | PIPERAZINE DERIVATIVES INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | UNIV PARIS 7 DENIS DIDEROT (FR) | 2002-09-18 | — | — | EP | disclosed |
| EP-1095029-A1 | PIPERAZINE DERIVATIVES INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | UNIVERSITE PARIS 7 - Denis DIDEROT (FR) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000001677-A1 | PIPERAZINE DERIVATIVES INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | UNIVERSITE PARIS 7 - DENIS DIDEROT (FR) | 2000-01-13 | — | — | WO | disclosed |