Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12126157 | 0.86 | KDM4C (0.41) | KDM4CNPC1RAB9AL3MBTL1CREBBP | |
| SCHEMBL15728474 | 0.76 | KDM4C (0.38) | KDM4CNPC1RAB9AL3MBTL1CREBBP | |
| SCHEMBL24006607 | 0.73 | KDM4C (0.41) | KDM4CNPC1RAB9AL3MBTL1CREBBP | |
| SCHEMBL12141797 | 0.73 | ICAM1 (0.42) | KDM4CNPC1RAB9AL3MBTL1CREBBP | |
| SCHEMBL17773643 | 0.71 | NPC1 (0.41) | KDM4CNPC1RAB9AL3MBTL1CREBBP | |
| SCHEMBL15728455 | 0.71 | KDM4C (0.35) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL25220812 | 0.71 | LMNA (0.43) | KDM4CRAB9AL3MBTL1CREBBPMEN1 | |
| SCHEMBL29447793 | 0.71 | KDM4C (0.40) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL23531793 | 0.70 | KDM4C (0.43) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL24195847 | 0.70 | KDM4C (0.39) | KDM4CNPC1RAB9AL3MBTL1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506747-B1 | Method of treating an inflammatory disease which comprises administering to a patient in need of such treatment-a N-(4-(5-Ethyl-3-pyridin-3-yl-pyrazol-1-yl)phenyl)pyridine-3-carboxamide; | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-01-14 | — | — | US | disclosed |
| WO-1999062885-A1 | SUBSTITUTED 1-(4-AMINOPHENYL)PYRAZOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |