Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | C1S | P09871 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7242045 | 0.87 | C1S (0.59) | KEAP1NFE2L2C1SALDH1A1LMNA | |
| SCHEMBL6926242 | 0.83 | C1S (0.56) | C1SALDH1A1PLAU | |
| SCHEMBL7246060 | 0.82 | CCR2 (0.52) | C1SPLAU | |
| SCHEMBL7245020 | 0.82 | C1S (0.50) | C1SPLAU | |
| SCHEMBL7242120 | 0.82 | C1S (0.65) | C1SALDH1A1SMN1; SMN2PLAU | |
| SCHEMBL6928674 | 0.82 | C1S (0.69) | C1SMEN1KMT2APLAU | |
| SCHEMBL6927266 | 0.81 | C1S (0.63) | C1S | |
| SCHEMBL6925664 | 0.81 | C1S (0.62) | C1SPLAU | |
| SCHEMBL6925869 | 0.80 | C1S (0.54) | C1SPLAU | |
| SCHEMBL7241070 | 0.80 | C1S (0.48) | C1SPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562840-B1 | Non-peptidic inhibitors of proteolytic enzymes such as urokinase | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-05-13 | — | — | US | claimed |