Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7245801 | 0.90 | SMN1; SMN2 (0.64) | F10KMT2AMEN1MAPTLMNA | |
| SCHEMBL5419665 | 0.87 | F10 (0.74) | F10KMT2AMEN1MAPTLMNA | |
| SCHEMBL7245758 | 0.86 | F10 (0.59) | F10KMT2AMEN1MAPTLMNA | |
| SCHEMBL3785256 | 0.86 | F10 (0.77) | F10KMT2AMEN1MAPTLMNA | |
| SCHEMBL7250878 | 0.85 | F10 (1.00) | F10KMT2AMEN1MAPTLMNA | |
| SCHEMBL30117892 | 0.84 | F10 (0.79) | F10KMT2AMEN1MAPTLMNA | |
| SCHEMBL3785860 | 0.84 | F10 (0.79) | F10KMT2AMEN1MAPTLMNA | |
| SCHEMBL3781363 | 0.83 | KDM4E (0.75) | F10KMT2AMEN1MAPTLMNA | |
| SCHEMBL3787237 | 0.83 | MAPT (0.68) | F10KMT2AMEN1MAPTLMNA | |
| SCHEMBL5423504 | 0.83 | MAPT (0.71) | F10KMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605626-B2 | Benzamide inhibitors of factor Xa | ELI LILLY AND COMPANY | 2003-08-12 | — | — | US | disclosed |
| US-20020120007-A1 | Benzamide inhibitors of factor Xa | BEIGHT DOUGLAS WADE (US) | 2002-08-29 | — | — | US | disclosed |
| US-6313122-B1 | AS INHIBITORS OF FACTOR XA AND ARE USED AS ANTICOAGULANTS IN MAMMALS | ELI LILLY AND COMPANY | 2001-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120007-A1 | Benzamide inhibitors of factor Xa | TFPI, F11, F12 | F10 12/4885KMT2A 2083/4885MEN1 1119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.