Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.65 |
| ▸ | GPR183 | P32249 | 8/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL724056 | 0.89 | HDAC1 (0.69) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL1486886 | 0.89 | HDAC1 (0.69) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL12152498 | 0.86 | LMNA (0.67) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL1486851 | 0.86 | KDM4E (0.62) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL726203 | 0.86 | KDM4E (0.62) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL723772 | 0.86 | HDAC1 (0.67) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL723773 | 0.86 | HDAC1 (0.67) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL724839 | 0.86 | HDAC1 (0.64) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL1486984 | 0.86 | HDAC1 (0.64) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL8241471 | 0.85 | HDAC6 (0.86) | HDAC1HDAC3HDAC4HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025155-A1 | HYDROXAMATE-BASED INHIBITORS OF DEACETYLASES | NOVARTIS AG (CH) | 2012-03-01 | — | — | WO | claimed |