SCHEMBL7244396

SCHEMBL7244396

O=C(S)CC1c2ccccc2COc2ccc(/C=C/c3ccc4ccc(Cl)cc4n3)cc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYSLTR1 Q9Y271 5/20 0.40
CYSLTR2 Q9NS75 4/20 0.40
GLA P06280 1/20 0.40
PTGER1 P34995 2/20 0.38
PTGER4 P35408 2/20 0.38
PTGER3 P43115 2/20 0.38
PTGER2 P43116 2/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ABCC1 P33527 2/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
NFKB1 P19838 1/20 0.36
MAPK1 P28482 1/20 0.36
RAB9A P51151 1/20 0.36
NFKB2 Q00653 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7244406 1.00 CYSLTR1 (0.40) CYSLTR1CYSLTR2GLAPTGER1PTGER4
SCHEMBL7244409 0.90 GLA (0.41) CYSLTR1CYSLTR2GLAPTGER1PTGER4
SCHEMBL7244400 0.90 GLA (0.41) CYSLTR1CYSLTR2GLAPTGER1PTGER4
SCHEMBL7248487 0.88 GLA (0.38) CYSLTR1CYSLTR2GLAKDM4ENPC1
SCHEMBL7248483 0.88 GLA (0.38) CYSLTR1CYSLTR2GLAKDM4ENPC1
SCHEMBL7243644 0.84 GLA (0.47) CYSLTR1CYSLTR2GLAMEN1KMT2A
SCHEMBL7243639 0.84 GLA (0.47) CYSLTR1CYSLTR2GLAMEN1KMT2A
SCHEMBL5332583 0.81 CYSLTR1 (0.43) CYSLTR1CYSLTR2MEN1KMT2AABCC1
SCHEMBL7251435 0.81 CYSLTR1 (0.52) CYSLTR1CYSLTR2MEN1KMT2AABCC1
SCHEMBL7251441 0.81 CYSLTR1 (0.52) CYSLTR1CYSLTR2MEN1KMT2AABCC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030216571-A1 Antiallergens; antiinflammatory agents UBE INDUSTRIES, LTD. (JP) 2003-11-20 US claimed
US-20030216571-A1 Antiallergens; antiinflammatory agents UBE INDUSTRIES, LTD. (JP) 2003-11-20 US disclosed
EP-1254897-A1 TRICYCLIC COMPOUNDS Ube Industries, Ltd. (JP) 2002-11-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216571-A1 Antiallergens; antiinflammatory agents CYSLTR2, CYSLTR1, LTC4S CYSLTR1 2/4885CYSLTR2 1/4885GLA 1201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.