SCHEMBL72445

SCHEMBL72445

ClCOC1Cc2ccccc2C1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.52
PNMT P11086 2/20 0.42
PRMT5 O14744 1/20 0.40
WDR77 Q9BQA1 1/20 0.40
SLC6A4 P31645 1/20 0.37
DRD3 P35462 1/20 0.35
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35
PLAU P00749 1/20 0.34
CYP19A1 P11511 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7255966 0.81 IDO1 (0.56) IDO1PNMTPRMT5WDR77DRD3
SCHEMBL13049209 0.77 IDO1 (0.52) IDO1PRMT5WDR77DRD3
SCHEMBL22051969 0.77 IDO1 (0.52) IDO1PNMTPRMT5WDR77DRD3
SCHEMBL23979090 0.74 IDO1 (0.48) IDO1PNMTPRMT5WDR77DRD3
SCHEMBL8349120 0.74 IDO1 (0.48) IDO1PRMT5WDR77DRD3
SCHEMBL9926587 0.74 IDO1 (0.48) IDO1PRMT5WDR77DRD3PLAU
SCHEMBL29599539 0.74 IDO1 (0.44) IDO1PRMT5WDR77MTNR1AMTNR1B
SCHEMBL24371021 0.74 IDO1 (0.44) IDO1PRMT5WDR77MTNR1AMTNR1B
SCHEMBL23963467 0.72 IDO1 (0.47) IDO1PRMT5WDR77DRD3
SCHEMBL23978878 0.72 IDO1 (0.47) IDO1PRMT5WDR77SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129086-B2 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-06 US disclosed
US-8129086-B2 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-06 US disclosed
US-8129086-B2 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-06 US disclosed
US-20090297979-A1 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed
US-20090297979-A1 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed
US-20090297979-A1 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090297979-A1 Polymerizable compound, polymer, positive resist composition, and patterning process using the same PRRC2A, PUF60, POLR2B IDO1 4883/4885PNMT 3415/4885PRMT5 757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.