SCHEMBL7245176

SCHEMBL7245176

Cc1ccc(CN2CCC(CCCC(=O)c3ccc4c(c3)CCNCC4)CC2)cc1

nearest known ligand 0.72

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACHE P22303 16/20 0.72
MCHR1 Q99705 2/20 0.55
FAAH O00519 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7227448 0.90 ACHE (0.71) ACHEMCHR1
Hydrochloric Acid SCHEMBL7234767 0.88 ACHE (0.66) ACHE
Hydrochloric Acid SCHEMBL7227577 0.88 ACHE (0.58) ACHEMCHR1FAAH
Hydrochloric Acid SCHEMBL7236495 0.87 ACHE (0.59) ACHEMCHR1FAAH
Hydrochloric Acid SCHEMBL7227835 0.86 ACHE (0.54) ACHEMCHR1FAAH
SCHEMBL7228023 0.85 ACHE (0.67) ACHEMCHR1FAAH
Hydrochloric Acid SCHEMBL7227836 0.84 ACHE (0.66) ACHEMCHR1FAAH
SCHEMBL9207777 0.84 ACHE (1.00) ACHE
Hydrochloric Acid SCHEMBL7227656 0.84 ACHE (0.53) ACHEMCHR1FAAH
Hydrochloric Acid SCHEMBL7245964 0.84 ACHE (0.60) ACHEFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6534496-B1 Prophylactic and/or therapeutic drug for obesity and obesity associated diseasestor diabetes with a reduced risk for central side effects and high universality in usage. Another object of the a lipolytic agent, or a prophylactic and/or TAKEDA CHEMICAL INDUSTRIES, INC. (JP) 2003-03-18 US disclosed
EP-0975624-A1 THERMOGENIC COMPOSITION AND BENZAZEPINE THERMOGENICS Takeda Chemical Industries, Ltd. (JP) 2000-02-02 EP disclosed
WO-1998046590-A1 THERMOGENIC COMPOSITION AND BENZAZEPINE THERMOGENICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-10-22 WO disclosed