Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7253898 | 0.94 | EDNRB (0.86) | EDNRBEDNRA | |
| SCHEMBL7250698 | 0.93 | EDNRB (0.82) | EDNRBEDNRA | |
| SCHEMBL7246598 | 0.91 | EDNRB (0.80) | EDNRBEDNRA | |
| SCHEMBL7251958 | 0.88 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL7248173 | 0.88 | EDNRB (0.82) | EDNRBEDNRA | |
| SCHEMBL7252235 | 0.87 | EDNRB (0.89) | EDNRBEDNRA | |
| SCHEMBL7245146 | 0.87 | EDNRB (0.88) | EDNRBEDNRA | |
| SCHEMBL7247318 | 0.86 | EDNRB (0.83) | EDNRBEDNRA | |
| SCHEMBL7252229 | 0.86 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL7252715 | 0.84 | EDNRB (1.00) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670367-B1 | Vasodilator; hypertension; surprisingly show antagonistic action on the neurokinin receptor; 2-(4-Methoxy-6-methyl-2-pyrimidinyloxy)-3-(2-(3,4- dimethoxyphenyl)ethoxy)-3,3-diphenylpropionic Acid | ABBOTT GMBH & CO., KG (DE) | 2003-12-30 | — | — | US | disclosed |
| EP-0929529-A2 | AZINYLOXY, AND PHENOXY-DIARYL-CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE AS MIXED ET A?/ET B? ENDOTHELIN RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998009953-A2 | AZINYLOXY-AND PHENOXY-DIARYL-CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE AS MIXED ETA/ETB ENDOTHELIN RECEPTOR ANTAGONISTS | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-12 | — | — | WO | disclosed |