Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 6/20 | 0.34 |
| ▸ | RAB9A | P51151 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722988 | 0.88 | FPR2 (0.39) | FPR2KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL720449 | 0.82 | MKNK1 (0.38) | FPR2KDM4ERAB9ASMN1; SMN2KMT2A | |
| SCHEMBL29642097 | 0.73 | IL2 (0.57) | KDM4ESMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL10201122 | 0.73 | IL2 (0.57) | KDM4ESMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL30534430 | 0.72 | STIM1 (0.38) | FPR2KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10201120 | 0.72 | STIM1 (0.53) | NPC1RAB9ASMN1; SMN2ESR1ESR2 | |
| SCHEMBL29642074 | 0.72 | STIM1 (0.53) | NPC1RAB9ASMN1; SMN2ESR1ESR2 | |
| SCHEMBL1701281 | 0.69 | GAA (0.41) | ESR1ESR2GAAL3MBTL1 | |
| SCHEMBL724532 | 0.69 | GAA (0.31) | KDM4ESMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL722987 | 0.68 | GAA (0.31) | SMN1; SMN2MAPTGAAL3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053210-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053210-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | ORAI1, SARAF, RYR2 | FPR2 1818/4885KDM4E 4057/4885NPC1 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.