Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.57 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | AHR | P35869 | 1/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.57 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637429 | 0.86 | ADORA2A (0.54) | ADORA2AADORA1KDM4EGPR35MEN1 | |
| SCHEMBL296469 | 0.78 | HRH4 (0.57) | KDM4EMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL2299730 | 0.78 | ADORA2A (0.59) | ADORA2AADORA1MEN1KMT2AGRIN2D | |
| Hydrochloric Acid SCHEMBL1878102 | 0.77 | HRH4 (0.56) | KDM4EMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL4343732 | 0.75 | ADORA2A (0.59) | ADORA2AADORA1MEN1KMT2AALDH1A1 | |
| SCHEMBL9694560 | 0.75 | ADORA1 (0.59) | ADORA2AADORA1KDM4EMEN1HPGD | |
| SCHEMBL28982785 | 0.74 | KDM4E (0.51) | ADORA2AADORA1KDM4EALDH1A1GAA | |
| SCHEMBL30211865 | 0.74 | KDM4E (0.51) | ADORA2AADORA1KDM4EALDH1A1GAA | |
| SCHEMBL3866419 | 0.74 | ADORA2A (1.00) | ADORA2AADORA1KDM4EHPGDCYP1A2 | |
| SCHEMBL30024159 | 0.74 | ALDH1A1 (0.45) | KDM4EGPR35MEN1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4956465-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | claimed |
| US-6653307-B2 | Such as N-(4-chlorobenzyl)-6-(4-morpholinylmethyl)-4-oxo-1-phenyl-1,4-dihydro-3-quinolinecarboxamide for treatment of herpes virus; viral DNA polymerase inhibitors | PHARMACIA & UPJOHN COMPANY | 2003-11-25 | — | — | US | disclosed |
| US-4956465-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |
| US-4956465-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |