Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.56 |
| ▸ | PIM1 | P11309 | 4/20 | 0.44 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.44 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.44 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | STK32B | Q9NY57 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.44 |
| ▸ | CYCS | P99999 | 3/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL28173578 | 0.85 | TOP1 (0.63) | TOP1CYCSENPP2TERTSTAT3 | |
| Quinoline SCHEMBL28121893 | 0.82 | TOP1 (0.60) | TOP1CYCSENPP2TERTSTAT3 | |
| SCHEMBL28008849 | 0.81 | TOP1 (0.72) | TOP1CYCSENPP2TERTSTAT3 | |
| SCHEMBL3999312 | 0.81 | TOP1 (0.72) | TOP1CYCSENPP2TERTSTAT3 | |
| SCHEMBL27899186 | 0.81 | TOP1 (0.72) | TOP1CYCSENPP2TERTSTAT3 | |
| SCHEMBL29962487 | 0.81 | TOP1 (0.72) | TOP1CYCSENPP2TERTSTAT3 | |
| SCHEMBL28022267 | 0.81 | TOP1 (0.72) | TOP1CYCSENPP2TERTSTAT3 | |
| SCHEMBL30616040 | 0.81 | TOP1 (0.72) | TOP1CYCSENPP2TERTSTAT3 | |
| SCHEMBL3424111 | 0.81 | TOP1 (0.81) | TOP1CYCSENPP2TERTSTAT3 | |
| Hydrochloric Acid SCHEMBL8203834 | 0.81 | CYP2A6 (0.59) | TOP1PIM1BMPR1BPIK3C2GCDKL5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105130-A1 | Thiaporphyrin, selenaporphyrin, and carotenoid porphyrin compounds as c-myc and telomerase inhibitors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105130-A1 | Thiaporphyrin, selenaporphyrin, and carotenoid porphyrin compounds as c-myc and telomerase inhibitors | MYCBP, MYC, TERF2IP | TOP1 132/4885PIM1 246/4885BMPR1B 2819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.