Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.62 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14268547 | 0.80 | KMT2A (0.61) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5224812 | 0.80 | NR1H4 (0.61) | CA1CA2NR1H4NPC1RAB9A | |
| SCHEMBL13762080 | 0.79 | KCNK9 (0.76) | KCNK9KCNK3CA1CA2NR1H4 | |
| SCHEMBL7295509 | 0.79 | KCNK9 (0.80) | KCNK9KCNK3CA1CA2NR1H4 | |
| SCHEMBL7301884 | 0.78 | PTGS1 (0.74) | KCNK9KCNK3CA1CA2NR1H4 | |
| SCHEMBL14195814 | 0.78 | KCNK9 (0.83) | KCNK9KCNK3CA1CA2NR1H4 | |
| SCHEMBL2664554 | 0.77 | KMT2A (0.77) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL21588759 | 0.76 | PTGS1 (0.72) | KCNK9KCNK3CA1CA2HDAC8 | |
| SCHEMBL13561213 | 0.76 | KCNK9 (0.83) | KCNK9KCNK3CA1CA2NR1H4 | |
| SCHEMBL21652317 | 0.75 | GRM5 (0.69) | NPC1RAB9ASMN1; SMN2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605626-B2 | Benzamide inhibitors of factor Xa | ELI LILLY AND COMPANY | 2003-08-12 | — | — | US | disclosed |
| US-20020120007-A1 | Benzamide inhibitors of factor Xa | BEIGHT DOUGLAS WADE (US) | 2002-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120007-A1 | Benzamide inhibitors of factor Xa | TFPI, F11, F12 | KCNK9 1168/4885KCNK3 2579/4885CA1 1970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.