⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9248112 | 0.86 | — | — | |
| SCHEMBL11568283 | 0.75 | — | — | |
| SCHEMBL22421602 | 0.72 | — | — | |
| SCHEMBL5093443 | 0.72 | — | — | |
| SCHEMBL15590204 | 0.72 | — | — | |
| SCHEMBL2441587 | 0.72 | — | — | |
| SCHEMBL5395731 | 0.72 | LMNA (0.31) | — | |
| SCHEMBL11607749 | 0.72 | LMNA (0.33) | — | |
| SCHEMBL9442088 | 0.70 | — | — | |
| SCHEMBL17852706 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6600028-B1 | Tricyclic compound for use as viricide | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2003-07-29 | — | — | US | disclosed |
| EP-0973788-A1 | TRICYCLIC BASE ANALOGUES | Amersham Pharmacia Biotech UK Limited (GB) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998043991-A1 | TRICYCLIC BASE ANALOGUES | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 1998-10-08 | — | — | WO | disclosed |
| US-5256815-A | Intermediates for herbicides and plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1993-10-26 | — | — | US | disclosed |
| US-5189227-A | Intermediates for cyclopropanecarbaldehydes | CIBA-GEIGY CORPORATION (US) | 1993-02-23 | — | — | US | disclosed |
| US-4968836-A | FROM A HYDROCARBYLOXY HALOGENATED TETRAHYDROFURAN | CIBA-GEIGY CORPORATION (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0381623-A1 | Process for the production of substituted cyclopropanals | CIBA-GEIGY AG (CH) | 1990-08-08 | — | — | EP | disclosed |