Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.67 |
| ▸ | PPARA | Q07869 | 12/20 | 0.67 |
| ▸ | FABP2 | P12104 | 2/20 | 0.67 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441192 | 0.83 | PPARG (0.76) | PPARGPPARAFABP2SLC22A12KMT2A | |
| SCHEMBL11400050 | 0.83 | PPARG (0.70) | PPARGPPARAFABP2SLC22A12KMT2A | |
| SCHEMBL11061399 | 0.81 | KMT2A (0.65) | KMT2AMAPTTDP1KDM4E | |
| Fenofibric Acid SCHEMBL16377 | 0.80 | PPARA (1.00) | PPARGPPARAFABP2SLC22A12KMT2A | |
| Fenofibric Acid SCHEMBL28478335 | 0.79 | PPARA (0.97) | PPARGPPARAFABP2SLC22A12KMT2A | |
| Fenofibric Acid SCHEMBL10967778 | 0.79 | PPARA (0.97) | PPARGPPARAFABP2SLC22A12KMT2A | |
| SCHEMBL11578249 | 0.79 | KMT2A (1.00) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28033215 | 0.79 | KMT2A (0.71) | KMT2AALDH1A1TDP1POLB | |
| SCHEMBL10489212 | 0.78 | KMT2A (0.75) | KMT2AMAPTALDH1A1TDP1POLB | |
| Fenofibric Acid SCHEMBL4756701 | 0.78 | PPARA (0.94) | PPARGPPARAFABP2SLC22A12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030119757-A1 | Methods for treating or preventing vascular inflammation using sterol absorption inhibitor(s) | SCHERING CORPORATION | 2003-06-26 | — | — | US | disclosed |
| EP-0012804-B2 | Salts of a non toxic, activated anion exchange resin capable of establishing a stable binding with bile acids and 2-(4'-(p-chlorobenzoyl)-phenoxy)-2-(methyl)-propionic acid and pharmaceutical compositions comprising these salts | ALFA FARMACEUTICI S.p.A. (IT) | 1987-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119757-A1 | Methods for treating or preventing vascular inflammation using sterol absorption inhibitor(s) | FABP2, CETP, PCSK9 | PPARG 482/4885PPARA 501/4885FABP2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.