Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.56 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4100742 | 0.91 | MAPK14 (0.68) | MAPK14 | |
| SCHEMBL13755665 | 0.73 | MAPK14 (0.87) | MAPK14MAPK11 | |
| SCHEMBL12729681 | 0.71 | MAPK14 (1.00) | MAPK14MAPK11 | |
| SCHEMBL1226894 | 0.69 | KDR (0.83) | — | |
| SCHEMBL13755666 | 0.69 | MAPK14 (0.54) | MAPK14MAPK11 | |
| SCHEMBL1226906 | 0.69 | KDR (0.82) | — | |
| SCHEMBL16576239 | 0.69 | MAPK14 (1.00) | MAPK14MAPK11 | |
| SCHEMBL12729611 | 0.69 | MAPK14 (0.67) | MAPK14MAPK11 | |
| SCHEMBL4045888 | 0.68 | KDR (0.65) | MAPK14 | |
| SCHEMBL14280412 | 0.68 | MAPK14 (1.00) | MAPK14MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670357-B2 | Antiinflammatory agents | BRISTOL-MYERS SQUIBB COMPANY | 2003-12-30 | — | — | US | disclosed |