Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27278218 | 0.97 | — | — | |
| SCHEMBL1100858 | 0.96 | — | — | |
| SCHEMBL26076 | 0.93 | — | — | |
| SCHEMBL4891349 | 0.93 | ALDH1A1 (0.46) | ALDH1A1CA2THRBTSHRLMNA | |
| SCHEMBL8758088 | 0.87 | — | — | |
| SCHEMBL15804715 | 0.87 | — | — | |
| SCHEMBL50322 | 0.87 | — | — | |
| SCHEMBL13195682 | 0.87 | — | — | |
| SCHEMBL33592 | 0.87 | — | — | |
| SCHEMBL17526573 | 0.84 | ALDH1A1 (0.52) | ALDH1A1CA2THRBTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2654788-B1 | GAS-FILLED MICROVESICLES FOR USE AS VACCINE | BRACCO SUISSE SA (CH) | 2018-03-14 | — | — | EP | disclosed |
| EP-2661500-A2 | CLOSTRIDIUM DIFFICILE ANTIGENS | Cangene Corporation (CA) | 2013-11-13 | — | — | EP | disclosed |
| EP-2654788-A1 | GAS-FILLED MICROVESICLES FOR USE AS VACCINE | Bracco Suisse S.A. (CH) | 2013-10-30 | — | — | EP | disclosed |
| WO-2013084070-A2 | SALMONELLA VACCINE PROTEINS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-06-13 | — | — | WO | disclosed |
| WO-2012092469-A2 | CLOSTRIDIUM DIFFICILE ANTIGENS | CANGENE CORPORATION (CA) | 2012-07-05 | — | — | WO | disclosed |
| WO-2012085072-A1 | GAS-FILLED MICROVESICLES FOR USE AS VACCINE | BRACCO SUISSE SA (CH) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012025831-A2 | SALMONELLA VACCINE PROTEINS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-03-01 | — | — | WO | disclosed |
| WO-2009012589-A1 | VACCINES AND METHODS FOR TREATMENT OR PREVENTION OF GRAM NEGATIVE BACTERIAL INFECTION IN A VERTEBRATE SUBJECT | UNIVERSITY OF SASKATCHEWAN (CA) | 2009-01-29 | — | — | WO | disclosed |
| EP-0981367-A1 | IMMUNIZATION AGAINST ENDOGENOUS MOLECULES | BIOSTAR INC. (CA) | 2000-03-01 | — | — | EP | disclosed |
| WO-1998034639-A1 | IMMUNIZATION AGAINST ENDOGENOUS MOLECULES | BIOSTAR INC. (CA) | 1998-08-13 | — | — | WO | disclosed |