Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | XBP1 | P17861 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542141 | 0.88 | UTS2R (0.49) | UTS2RFABP4LMNAALDH1A1MAPT | |
| SCHEMBL6543128 | 0.86 | UTS2R (0.47) | UTS2RFABP4LMNAALDH1A1MAPT | |
| SCHEMBL6542775 | 0.85 | UTS2R (0.52) | UTS2RFABP4LMNAALDH1A1MAPT | |
| SCHEMBL6542898 | 0.84 | UTS2R (0.51) | UTS2RFABP4LMNAALDH1A1MAPT | |
| Sb611812 SCHEMBL6542569 | 0.83 | UTS2R (0.53) | UTS2RFABP4LMNAALDH1A1MAPT | |
| SCHEMBL6542669 | 0.81 | UTS2R (0.53) | UTS2RFABP4LMNAALDH1A1MAPT | |
| SCHEMBL6542559 | 0.81 | PPARG (0.48) | UTS2RLMNAALDH1A1MAPTHTT | |
| SCHEMBL6542576 | 0.81 | UTS2R (0.60) | UTS2RLMNAALDH1A1MAPTHTT | |
| SCHEMBL6541903 | 0.81 | LMNA (0.51) | UTS2RFABP4LMNAALDH1A1MAPT | |
| SCHEMBL6541457 | 0.81 | SMN1; SMN2 (0.59) | UTS2RFABP4LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030100580-A1 | Urotensin-II receptor antagonists | SMITHKLINE BEECHAM CORPORATION | 2003-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100580-A1 | Urotensin-II receptor antagonists | UTS2R, TMPRSS4, PLAUR | UTS2R 1/4885FABP4 2008/4885LMNA 4591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.