Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7248148 | 0.94 | MEN1 (0.64) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL24704034 | 0.90 | MEN1 (0.70) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL648889 | 0.90 | MEN1 (0.70) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL7527305 | 0.90 | MEN1 (0.70) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL14970302 | 0.84 | KMT2A (0.55) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL6934839 | 0.83 | MEN1 (0.57) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL6934835 | 0.83 | MEN1 (0.57) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL3218584 | 0.79 | MAPT (1.00) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL10728016 | 0.79 | ALDH1A1 (0.54) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL6170117 | 0.79 | MEN1 (0.62) | MAPTMEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6590102-B1 | Hydrogenation of 2-cyano-3-(p-fluorophenyl)glutaric acid diethyl ester in the presence of catalysts to prepare isomer mixtures of ethyl 4-(p-fluorophenyl)-6-oxo-3-piperidine -carboxylate, used as intermediates of paroxetine | ASAHI GLASS COMPANY LTD. (JP) | 2003-07-08 | — | — | US | disclosed |
| US-6476228-B1 | Process for producing piperidinecarbinols | ASAHI GLASS COMPANY LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-0802185-B1 | Process for producing piperidinecarbinols | ASAHI GLASS CO LTD (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-6197960-B1 | REDUCTION OF CYANOGLUTARIC ACID; CYCLIZATION, ISOMERIZATION | ASAHI GLASS COMPANY LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0802185-A1 | Process for producing piperidinecarbinols | ASAHI GLASS COMPANY LTD. (JP) | 1997-10-22 | — | — | EP | disclosed |