Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492158 | 0.90 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1EPHX2LMNA | |
| SCHEMBL27495686 | 0.87 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1EPHX2LMNA | |
| SCHEMBL27494516 | 0.87 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1EPHX2LMNA | |
| SCHEMBL27494515 | 0.87 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1EPHX2LMNA | |
| SCHEMBL22273545 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1EPHX2LMNA | |
| SCHEMBL27494517 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1EPHX2LMNA | |
| SCHEMBL5033585 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1EPHX2LMNA | |
| SCHEMBL22273547 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1EPHX2LMNA | |
| SCHEMBL22273546 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1EPHX2LMNA | |
| SCHEMBL17381371 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1EPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512000-B1 | Aminocarbonyl- substituted benzimidazole derivatives for the treatment of diseases in which inhibition of tryptase is of therapeutic such as for treating an inflammatory or allergic disease | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-01-28 | — | — | US | disclosed |