Foscarnet

Foscarnet

SCHEMBL7249084

O=C(O)P(=O)(O)O.[NaH].[NaH]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Foscarnet SCHEMBL8169999 1.00 BLM (0.39)
Foscarnet SCHEMBL2689694 1.00
Foscarnet SCHEMBL7637 1.00 BLM (0.39)
Foscarnet SCHEMBL5058619 1.00 BLM (0.39)
Foscarnet SCHEMBL3678731 0.96 MEN1 (0.37)
Foscarnet SCHEMBL8862809 0.96 MEN1 (0.37)
Foscarnet SCHEMBL3966747 0.96 MEN1 (0.37)
Foscarnet SCHEMBL8647698 0.95 BLM (0.41)
Foscarnet SCHEMBL23633 0.95
Foscarnet SCHEMBL15531347 0.95 BLM (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957320-A Organic sodium phosphonate carboxylate development accelerator and preparation method thereof 南阳柯丽尔科技有限公司 2022-08-30 CN disclosed
US-6555663-B1 Pharmaceuticals which are activated intracellularly by reaction with cellular electron carriers or free radicals to cause release of a free and active drug molecule MILLS RANDELL LEE (US) 2003-04-29 US disclosed
EP-0414730-B1 Chemical Compounds and pharmaceutical compositions capable of releasing a drug MILLS RANDELL L (US) 1999-12-15 EP disclosed
US-5773592-A COMPRISES A CHEMILUMINESCENT MOIETY, A PHOTOCHROMIC MOIETY AND A BIOLOGICALLY ACTIVE AGENT CAPABLE OF BEING RELEASED MILLS RANDELL LEE (US) 1998-06-30 US disclosed
US-5428163-A Luminides; chemiluminescence; redox system, releasing free drug MILLS RANDELL L (US) 1995-06-27 US disclosed
EP-0414730-A4 LUMINIDE AND MACROLUMINIDE CLASS OF PHARMACEUTICALS 1993-06-16 EP disclosed
EP-0414730-A1 LUMINIDE AND MACROLUMINIDE CLASS OF PHARMACEUTICALS Mills, Randell L. (US) 1991-03-06 EP disclosed
WO-1989009833-A1 LUMINIDE AND MACROLUMINIDE CLASS OF PHARMACEUTICALS MILLS RANDELL L (US) 1989-10-19 WO disclosed