Foscarnet

Foscarnet

SCHEMBL8647698

O=C(O)P(=O)(O)O.O=C(O)P(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
LMNA P02545 2/20 0.41
MEN1 O00255 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
KMT2A Q03164 1/20 0.41
MMP2 P08253 7/20 0.39
MMP8 P22894 5/20 0.39
MMP3 P08254 4/20 0.39
CA2 P00918 4/20 0.39
CA1 P00915 3/20 0.36
CA9 Q16790 3/20 0.36
SLC34A1 Q06495 1/20 0.36
MMP1 P03956 4/20 0.33
MMP9 P14780 3/20 0.33
CA12 O43570 2/20 0.33
KDM4E B2RXH2 1/20 0.33
THRB P10828 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Foscarnet SCHEMBL15531347 1.00 BLM (0.41) BLMTDP1LMNAMEN1HPGD
Foscarnet SCHEMBL23633 1.00
Foscarnet SCHEMBL4538550 0.95
Foscarnet SCHEMBL8854374 0.95
Foscarnet SCHEMBL7249084 0.95
Foscarnet SCHEMBL10700003 0.95
Foscarnet SCHEMBL5058619 0.95 BLM (0.39) BLMTDP1LMNAMEN1HPGD
Foscarnet SCHEMBL8169999 0.95 BLM (0.39) BLMTDP1LMNAMEN1HPGD
Foscarnet SCHEMBL11596760 0.95
Foscarnet SCHEMBL8863102 0.95 BLM (0.39) BLMTDP1LMNAMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020138402-A1 ANTIVIRAL AGENT FOR TREATING OR PREVENTING ALZHEIMER'S DISEASE AND USE THEREOF クリニジェン株式会社 2020-07-02 WO disclosed
CN-110074968-A Coat packaging materials SIO2医药产品公司 2019-08-02 CN disclosed
CN-105392916-B Coated packaging material SIO2医药产品公司 2019-03-08 CN disclosed
CN-107592807-A Cyclic olefin polymer container with damage resistant and anlistatig coating SIO2医药产品公司 2018-01-16 CN disclosed
US-5773027-A HUMAN IMMUNODEFICIENCY VIRUS AND CYTOMEGALOVIRUS Bergeron, Michael G. (CA) 1998-06-30 US disclosed