Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4249546 | 0.86 | HRH1 (0.56) | HRH1LMNACYP1A2CYP2C19SMN1; SMN2 | |
| Water SCHEMBL27667215 | 0.79 | LMNA (0.57) | HRH1LMNACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL1273198 | 0.79 | HRH1 (0.51) | HRH1LMNACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL865443 | 0.79 | LMNA (0.57) | HRH1LMNACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL1273199 | 0.79 | LMNA (0.57) | HRH1LMNACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL4184428 | 0.79 | HRH1 (0.57) | HRH1LMNACYP1A2TDP1ALDH1A1 | |
| SCHEMBL28982964 | 0.78 | LMNA (0.55) | HRH1LMNACYP1A2CYP2C19SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL28869767 | 0.78 | LMNA (0.55) | HRH1LMNACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL4063300 | 0.77 | HRH1 (0.55) | HRH1LMNACYP1A2TDP1ALDH1A1 | |
| Potassium SCHEMBL4063307 | 0.77 | HRH1 (0.55) | HRH1LMNACYP1A2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030078251-A1 | Benzoxazepinones and their use as squalene synthase inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2003-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078251-A1 | Benzoxazepinones and their use as squalene synthase inhibitors | SQLE, CYP17A1, ACOX1 | HRH1 608/4885LMNA 2609/4885CYP1A2 380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.