Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.62 |
| ▸ | CCNC | P24863 | 2/20 | 0.52 |
| ▸ | CDK8 | P49336 | 2/20 | 0.52 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064675 | 0.87 | CCNC (0.53) | ADORA2ACCNCCDK8CDK19DRD2 | |
| SCHEMBL7244853 | 0.86 | CCNC (0.56) | ADORA2ACCNCCDK8CDK19DRD2 | |
| SCHEMBL7063434 | 0.85 | CCNC (0.71) | ADORA2ACCNCCDK8CDK19DRD2 | |
| SCHEMBL7249311 | 0.84 | CCNC (0.54) | ADORA2ACCNCCDK8CDK19DRD2 | |
| SCHEMBL7041432 | 0.84 | CCNC (0.46) | ADORA2ACCNCCDK8CDK19DRD2 | |
| SCHEMBL7243399 | 0.82 | CCNC (0.50) | ADORA2ACCNCCDK8CDK19DRD2 | |
| SCHEMBL7096219 | 0.82 | CCNC (0.56) | ADORA2ACCNCCDK8CDK19DRD2 | |
| SCHEMBL7243829 | 0.82 | CCNC (0.56) | CCNCCDK8CDK19DRD2DRD4 | |
| SCHEMBL7242256 | 0.81 | CCNC (0.58) | ADORA2ACCNCCDK8CDK19DRD2 | |
| SCHEMBL7246960 | 0.80 | CCNC (0.52) | ADORA2ACCNCCDK8CDK19DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030158245-A1 | Fused heterocyclic derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158245-A1 | Fused heterocyclic derivatives, their production and use | TST, STS, AHR | ADORA2A 1243/4885CCNC 2012/4885CDK8 3614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.