Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30236601 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRCA12CA1 | |
| SCHEMBL1897857 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRCA12CA1 | |
| SCHEMBL29687732 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRCA12CA1 | |
| SCHEMBL527946 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRCA12CA1 | |
| SCHEMBL16128763 | 0.85 | HSD17B10 (0.51) | ALDH1A1TDP1TSHRCA12CA1 | |
| SCHEMBL15974099 | 0.85 | ALDH1A1 (0.49) | ALDH1A1TDP1TSHRCA12CA1 | |
| SCHEMBL18117631 | 0.85 | ALDH1A1 (0.41) | ALDH1A1TDP1TSHRCA12CA1 | |
| SCHEMBL2649866 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRCA12CA1 | |
| SCHEMBL18797069 | 0.85 | CYP3A4 (0.51) | ALDH1A1TDP1TSHRCYP3A4GPR35 | |
| SCHEMBL14746570 | 0.85 | HSD17B10 (0.51) | ALDH1A1TDP1TSHRGPR35MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6630577-B2 | Useful for producing bioconjugates | PROLINX, INC. | 2003-10-07 | — | — | US | disclosed |
| EP-1264833-A2 | 1,2-Phenylenediboronic acid reagents and complexes | PROLINX, INC. (US) | 2002-12-11 | — | — | EP | disclosed |
| US-20020038004-A1 | 1,2-phenylenediboronic acid reagents and complexes | PROLINX, INC. | 2002-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020038004-A1 | 1,2-phenylenediboronic acid reagents and complexes | BCR, MGST1, SULT1E1 | ALDH1A1 526/4885TDP1 4196/4885TSHR 775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.