Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 20/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7392887 | 0.94 | FKBP1A (1.00) | FKBP1A | |
| SCHEMBL5966109 | 0.83 | FKBP1A (1.00) | FKBP1A | |
| SCHEMBL10031767 | 0.82 | FKBP1A (0.79) | FKBP1A | |
| SCHEMBL7807355 | 0.82 | FKBP1A (0.79) | FKBP1A | |
| SCHEMBL10031758 | 0.81 | FKBP1A (0.78) | FKBP1A | |
| SCHEMBL10031803 | 0.81 | FKBP1A (0.78) | FKBP1A | |
| SCHEMBL7814328 | 0.81 | FKBP1A (0.78) | FKBP1A | |
| SCHEMBL7978726 | 0.80 | FKBP1A (0.64) | FKBP1A | |
| SCHEMBL7978725 | 0.80 | FKBP1A (0.64) | FKBP1A | |
| SCHEMBL28331561 | 0.79 | FKBP1A (0.74) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6544976-B1 | Treating disorders characterized by neuronal damage caused by disease or trauma, such as Parkinson's disease, Alzheimer's disease, stroke, multiple sclerosis, amyotrophic lateral sclerosis, diabetic neuropathy and Bell's palsy. | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-04-08 | — | — | US | disclosed |