Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.56 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.56 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.56 |
| ▸ | PDE5A | O76074 | 1/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15700137 | 0.88 | ACHE (0.80) | ACHEPDE4D | |
| SCHEMBL7245357 | 0.83 | CYP24A1 (0.80) | ACHECYP19A1CYP26A1CYP24A1HTR2B | |
| SCHEMBL7249809 | 0.83 | CYP19A1 (0.80) | CYP19A1CYP26A1CYP24A1HTR2BSIGMAR1 | |
| SCHEMBL10427023 | 0.81 | KDM4E (0.49) | ACHECYP24A1FAAHABCC4CACNA1F | |
| SCHEMBL14491004 | 0.80 | ACHE (0.73) | ACHEFAAHABCC4CACNA1FPDE5A | |
| Bromide SCHEMBL17313369 | 0.79 | ACHE (0.77) | ACHE | |
| SCHEMBL7272223 | 0.79 | CHRNA7 (0.51) | ACHEFAAHABCC4CACNA1FPDE5A | |
| SCHEMBL7281372 | 0.79 | CHRNA7 (0.51) | ACHEFAAHABCC4CACNA1FPDE5A | |
| SCHEMBL7895132 | 0.78 | ACHE (1.00) | ACHE | |
| Bromide SCHEMBL17313325 | 0.78 | ACHE (0.76) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030191279-A1 | Urea derivatives useful as anticancer agents | GOLDSTEIN STEVEN WAYNE (US) | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191279-A1 | Urea derivatives useful as anticancer agents | CCNA1, CCNE1, CCND1 | ACHE 4694/4885CYP19A1 2314/4885CYP26A1 2627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.