Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | CCNC | P24863 | 11/20 | 0.35 |
| ▸ | CDK8 | P49336 | 11/20 | 0.35 |
| ▸ | CDK19 | Q9BWU1 | 11/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7247769 | 0.93 | DRD4 (0.38) | DRD4CCNCCDK8CDK19SMN1; SMN2 | |
| SCHEMBL7241267 | 0.90 | ADORA2A (0.39) | DRD4CCNA2CDK2CCNA1SMN1; SMN2 | |
| SCHEMBL7248713 | 0.83 | CCNC (0.53) | DRD4CCNCCDK8CDK19CCNA2 | |
| SCHEMBL7248643 | 0.77 | DRD4 (0.44) | DRD4CCNCCDK8CDK19IKBKB | |
| SCHEMBL7249485 | 0.76 | CCNC (0.50) | CCNCCDK8CDK19CDK9 | |
| SCHEMBL7243383 | 0.73 | CCNC (0.41) | DRD4CCNCCDK8CDK19CCNA2 | |
| SCHEMBL7249475 | 0.72 | CCNC (0.41) | DRD4CCNCCDK8CDK19AURKA | |
| SCHEMBL7246693 | 0.71 | DRD4 (0.67) | DRD4CCNCCDK8CDK19CDK9 | |
| SCHEMBL7241345 | 0.71 | CCNC (0.50) | DRD4CCNCCDK8CDK19CCNA2 | |
| SCHEMBL7242282 | 0.71 | CCNC (0.40) | DRD4CCNCCDK8CDK19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030158245-A1 | Fused heterocyclic derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158245-A1 | Fused heterocyclic derivatives, their production and use | TST, STS, AHR | DRD4 567/4885CCNC 2012/4885CDK8 3614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.