Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 11/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3858305 | 0.69 | PIM1 (0.62) | PIM1 | |
| SCHEMBL14458217 | 0.64 | APP (0.44) | PIM1 | |
| SCHEMBL13486991 | 0.61 | LCK (0.47) | PIM1 | |
| SCHEMBL4936010 | 0.60 | PIM1 (0.57) | PIM1 | |
| SCHEMBL29309667 | 0.58 | TDP1 (0.37) | — | |
| SCHEMBL13977543 | 0.58 | MMP2 (0.52) | — | |
| SCHEMBL15149812 | 0.57 | — | — | |
| SCHEMBL14303429 | 0.57 | — | — | |
| SCHEMBL13481387 | 0.57 | GLA (0.35) | — | |
| SCHEMBL7959821 | 0.55 | UPP1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670377-B1 | Inhibitory properties of human immunodeficiency virus integrase | CENTRE NATIONAL DE LA RECHERCHE (FR) | 2003-12-30 | — | — | US | disclosed |