Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28725778 | 0.87 | GSTP1 (0.40) | GSTP1MAPTHCAR2ATMALDH1A1 | |
| SCHEMBL11054119 | 0.85 | GSTP1 (0.39) | GSTP1MAPTHCAR2ATMALDH1A1 | |
| SCHEMBL13220390 | 0.83 | AKT1 (0.42) | HCAR2 | |
| SCHEMBL656055 | 0.81 | GSTP1 (0.37) | GSTP1MAPTHCAR2ATMCACNA1B | |
| SCHEMBL13244979 | 0.80 | MAPT (0.34) | GSTP1MAPTHCAR2ATMALDH1A1 | |
| SCHEMBL12785471 | 0.79 | GSTP1 (0.36) | GSTP1MAPTHCAR2ATMCACNA1B | |
| SCHEMBL7746005 | 0.79 | MAPT (0.39) | MAPTHCAR2ATMALDH1A1CACNA1B | |
| SCHEMBL25405174 | 0.79 | HCAR2 (0.40) | GSTP1HCAR2ALDH1A1 | |
| SCHEMBL16505 | 0.79 | HCAR2 (0.40) | GSTP1HCAR2ALDH1A1 | |
| SCHEMBL25405178 | 0.79 | HCAR2 (0.40) | GSTP1HCAR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030129428-A1 | MULTILAYER POLYAMIDE FILM STRUCTURES | WILMINGTON TRUST COMPANY | 2003-07-10 | — | — | US | claimed |
| EP-0904198-A1 | MULTILAYER POLYAMIDE FILM STRUCTURES | AlliedSignal Inc. (US) | 1999-03-31 | — | — | EP | claimed |
| WO-1997047468-A1 | MULTILAYER POLYAMIDE FILM STRUCTURES | ALLIEDSIGNAL INC. (US) | 1997-12-18 | — | — | WO | claimed |
| WO-1997028165-A1 | DERIVATIVES OF CAMPTOTHECIN FOR USE IN TREATING CANCER | THE STEHLIN FOUNDATION FOR CANCER RESEARCH (US) | 1997-08-07 | — | — | WO | disclosed |