SCHEMBL7746005

SCHEMBL7746005

CC=CCOC(=O)C=CCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.39
HCAR2 Q8TDS4 5/20 0.38
ATM Q13315 1/20 0.38
ALDH1A1 P00352 3/20 0.35
NR1I2 O75469 1/20 0.33
PGR P06401 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
PTGS2 P35354 1/20 0.33
PDE4D Q08499 1/20 0.33
CYP3A4 P08684 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
FFAR1 O14842 1/20 0.31
CYP19A1 P11511 1/20 0.31
RXRA P19793 1/20 0.31
PPARG P37231 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28417828 0.87 HCAR2 (0.43) MAPTHCAR2ATMALDH1A1CACNA1B
SCHEMBL27801168 0.85 GSTP1 (0.39) MAPTHCAR2ATMALDH1A1CACNA1B
SCHEMBL11054119 0.85 GSTP1 (0.39) MAPTHCAR2ATMALDH1A1CACNA1B
SCHEMBL8672035 0.83 HCAR2 (0.57) MAPTHCAR2ATMALDH1A1RAB9A
SCHEMBL8765629 0.80 HCAR2 (0.46) MAPTHCAR2ATMALDH1A1NR1I2
SCHEMBL7250372 0.79 GSTP1 (0.36) MAPTHCAR2ATMALDH1A1CACNA1B
SCHEMBL2469637 0.79 HCAR2 (0.57) MAPTHCAR2ATMALDH1A1TSHR
SCHEMBL4799130 0.79 MAPT (0.52) MAPTHCAR2ATMALDH1A1CYP3A4
SCHEMBL6050194 0.79 MAPT (0.52) MAPTHCAR2ATMALDH1A1CYP3A4
SCHEMBL27630882 0.79 HCAR2 (0.54) MAPTHCAR2ATMALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001053249-A1 PROCESS FOR THE CARBONYLATION OF BUTADIENE AND/OR AT LEAST ONE BUTADIENE DERIVATIVE DSM N.V. (NL) 2001-07-26 WO disclosed
EP-1118607-A1 Process for the carbonylation of butadiene and/or at least one butadiene derivative DSM N.V. (NL) 2001-07-25 EP disclosed
WO-2001021569-A1 PROCESS FOR THE PREPARATION OF 3-PENTENOIC ACID AND/OR ESTER THEREOF STARTING FROM BUTADIENE DSM N.V. (NL) 2001-03-29 WO disclosed
EP-1085004-A1 Process for the carbonylation of butadiene and/or butadiene derivative DSM N.V. (NL) 2001-03-21 EP disclosed