SCHEMBL725078

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL723277	0.95	MAP3K11 (0.50)	MAP3K11FYNMEN1KMT2ATDO2
	SCHEMBL771403	0.91	KMT2A (0.54)	MEN1KMT2AGAKCYP3A4CYP2D6
	SCHEMBL724718	0.82	PDE3B (0.46)	MEN1KMT2AMAPK14SCN9A
	SCHEMBL21951883	0.81	KMT2A (0.53)	MEN1KMT2ATDO2IDO1GAK
	SCHEMBL12224207	0.80	MEN1 (0.57)	MAP3K11MEN1KMT2ASCN9ABRD4
	SCHEMBL28525140	0.78	SYK (0.52)	MEN1KMT2AGAKCYP3A4CYP2D6
	SCHEMBL17732363	0.78	MEN1 (0.43)	MEN1KMT2AGAKBRD4
	SCHEMBL723823	0.76	MAP3K11 (0.59)	MAP3K11MEN1KMT2AGAKSCN9A
	SCHEMBL723813	0.76	GAK (0.49)	MAP3K11GAKBRD4
	SCHEMBL804651	0.76	TUBB4A (0.47)	MEN1KMT2AMAPK14PDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.