Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.57 |
| ▸ | PPARG | P37231 | 10/20 | 0.57 |
| ▸ | PPARD | Q03181 | 2/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289392 | 1.00 | PPARA (0.57) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL5228193 | 1.00 | PPARA (0.57) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL8977885 | 0.88 | CTSS (0.52) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL949023 | 0.88 | PPARA (0.56) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL949696 | 0.88 | PPARA (0.56) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL4671738 | 0.87 | PPARA (0.64) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL5142486 | 0.87 | PPARA (0.64) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL4671732 | 0.87 | PPARA (0.64) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL5226599 | 0.85 | JAK3 (0.51) | PPARAPPARGPPARDCTSSCTSK | |
| SCHEMBL8163842 | 0.83 | PPARA (0.55) | PPARAPPARGPPARDCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6632826-B1 | Carbocyclic HIV protease inhibitors | HOFFMANN-LA ROCHE INC. | 2003-10-14 | — | — | US | disclosed |