Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 3/20 | 0.37 |
| ▸ | HK1 | P19367 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021802 | 0.94 | KDM4E (0.41) | KDM4ERAB9AMAPTNPC1TDP1 | |
| Iodide SCHEMBL5892501 | 0.76 | KDM4E (0.43) | KDM4ERAB9AMAPTNPC1TDP1 | |
| SCHEMBL7254059 | 0.74 | KDM4E (0.53) | KDM4ERAB9AMAPTNPC1TDP1 | |
| Perchlorate SCHEMBL7256390 | 0.71 | KDM4E (0.50) | KDM4ERAB9AMAPTNPC1TDP1 | |
| SCHEMBL8385263 | 0.69 | KDM4E (0.50) | KDM4ERAB9AMAPTNPC1TDP1 | |
| SCHEMBL25672214 | 0.68 | CYP2A6 (0.39) | KDM4ERAB9ATDP1MEN1KMT2A | |
| SCHEMBL4626775 | 0.66 | — | — | |
| SCHEMBL1046351 | 0.64 | MEN1 (0.48) | KDM4ERAB9AMAPTNPC1TDP1 | |
| SCHEMBL4830357 | 0.64 | KDM4E (0.55) | KDM4ERAB9AMAPTTDP1MEN1 | |
| Iodide SCHEMBL1776694 | 0.63 | MEN1 (0.50) | KDM4ERAB9AMAPTNPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6635090-B1 | Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative | L'OREAL, S.A. (FR) | 2003-10-21 | — | — | US | claimed |