Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.45 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415949 | 0.88 | CHRM2 (0.67) | CHRM2ALDH1A1SMN1; SMN2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL7695180 | 0.85 | CHRM2 (0.64) | CHRM2ALDH1A1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL107396 | 0.85 | — | — | |
| SCHEMBL626104 | 0.85 | PNMT (0.50) | CHRM2ALDH1A1MAOBTAAR1TPSAB1 | |
| SCHEMBL11953353 | 0.84 | CHRM2 (0.57) | CHRM2ALDH1A1MAOBSMN1; SMN2CYP2C9 | |
| Hydrochloric Acid SCHEMBL9479829 | 0.83 | CHRM2 (0.61) | CHRM2ALDH1A1SMN1; SMN2CYP2C9CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL9177329 | 0.83 | MAOB (0.61) | MAOBTAAR1PNMTHRH3 | |
| Hydrochloric Acid SCHEMBL927415 | 0.83 | MAOB (0.65) | MAOBTAAR1PNMTHRH3 | |
| Iodide SCHEMBL29120576 | 0.83 | MAOB (0.61) | MAOBTAAR1PNMTHRH3 | |
| Bromide SCHEMBL31513717 | 0.83 | MAOB (0.61) | MAOBTAAR1PNMTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512000-B1 | Aminocarbonyl- substituted benzimidazole derivatives for the treatment of diseases in which inhibition of tryptase is of therapeutic such as for treating an inflammatory or allergic disease | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-01-28 | — | — | US | disclosed |