Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.44 |
| ▸ | PPARA | Q07869 | 16/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7248697 | 0.91 | PPARG (0.54) | PPARGPPARA | |
| SCHEMBL7252068 | 0.89 | PPARG (0.44) | PPARGPPARAPTPN1 | |
| SCHEMBL7247847 | 0.82 | PPARA (0.51) | PPARGPPARA | |
| SCHEMBL7248448 | 0.79 | PPARG (0.56) | PPARGPPARA | |
| SCHEMBL7252106 | 0.78 | PPARA (0.48) | PPARGPPARA | |
| SCHEMBL5389840 | 0.74 | PPARG (0.65) | PPARGPPARA | |
| SCHEMBL7248330 | 0.72 | PPARA (0.59) | PPARGPPARA | |
| SCHEMBL5992928 | 0.71 | PPARG (0.76) | PPARGPPARA | |
| SCHEMBL29163290 | 0.70 | PPARG (0.65) | PPARGPPARAPTPN1 | |
| SCHEMBL5385563 | 0.69 | PPARG (0.71) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664411-B2 | Beta-aryl/alpha-oxysubstituted alkylcarboxylic acids of 4-oxo-or thiocarbonylchromenes or thiochromenes; antiobesity, -cholesterol - diabetic agents; agonists of peroxisome proliferator activated receptors; kidney disorders | DR. REDDY'S LABORATORIES LIMITED (IN) | 2003-12-16 | — | — | US | disclosed |
| US-6331627-B1 | Intermediates of benzoxazinone derivatives and preparation thereof | REDDY'S LABORATORIES LTD. (IN) | 2001-12-18 | — | — | US | disclosed |
| EP-1124807-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2001-08-22 | — | — | EP | disclosed |
| US-6130214-A | Benzothiazin and benzoxazin derivatives; their preparation and uses | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-10-10 | — | — | US | disclosed |
| WO-1999016758-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-04-08 | — | — | WO | disclosed |