SCHEMBL7252106

SCHEMBL7252106

CCOC(Cc1ccc(OCC2NC(=O)c3ccccc3N2)cc1)C(=O)OC

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 16/20 0.48
PPARG P37231 16/20 0.48
PPARD Q03181 9/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7248330 0.90 PPARA (0.59) PPARAPPARGPPARD
SCHEMBL7252068 0.88 PPARG (0.44) PPARAPPARGPPARD
SCHEMBL7254305 0.87 PPARA (0.42) PPARAPPARGPPARD
SCHEMBL7254951 0.82 PPARA (0.46) PPARAPPARGPPARD
SCHEMBL7254345 0.82 PPARG (0.48) PPARAPPARGPPARD
SCHEMBL7248300 0.81 PPARA (0.45) PPARAPPARGPPARD
SCHEMBL7248448 0.80 PPARG (0.56) PPARAPPARG
SCHEMBL7251862 0.78 PPARG (0.44) PPARAPPARG
SCHEMBL7254839 0.77 PPARG (0.54) PPARAPPARGPPARD
SCHEMBL7249265 0.77 PPARA (0.45) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6664411-B2 Beta-aryl/alpha-oxysubstituted alkylcarboxylic acids of 4-oxo-or thiocarbonylchromenes or thiochromenes; antiobesity, -cholesterol - diabetic agents; agonists of peroxisome proliferator activated receptors; kidney disorders DR. REDDY'S LABORATORIES LIMITED (IN) 2003-12-16 US disclosed
US-6331627-B1 Intermediates of benzoxazinone derivatives and preparation thereof REDDY'S LABORATORIES LTD. (IN) 2001-12-18 US disclosed
EP-1124807-A1 NOVEL HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DR. REDDY'S RESEARCH FOUNDATION (IN) 2001-08-22 EP disclosed
US-6130214-A Benzothiazin and benzoxazin derivatives; their preparation and uses DR. REDDY'S RESEARCH FOUNDATION (IN) 2000-10-10 US disclosed
WO-1999016758-A1 NOVEL HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DR. REDDY'S RESEARCH FOUNDATION (IN) 1999-04-08 WO disclosed